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NPs smaller than 3 m can be internalized into non-phagocytic cells via non-specific endocytosis (29), while the maximum particle size available for endocytosis increases to 5 m (19), facilitated by the abundant M cells in the intestinal Peyer's patches (21) and aided by the intestinal mucosal membranes (30,31)

R., Pawlick R

Thus, pulmonary rehabilitation programs that avoid overtraining appear to be desirable in order to keep the increase in oxidative stress to a minimum and to efficiently induce antioxidant capacity during the pulmonary rehabilitation of COPD patients