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Parrella E, Maxim T, Maialetti F, Zhang L, Wan J, Wei M, Cohen P, Fontana L, Longo VD (2013) Protein restriction cycles reduce IGF-1 and phosphorylated Tau, and improve behavioral performance in an Alzheimers disease mouse model

The newly recruited monocytes express a pro-inflammatory phenotype (Ly6C hi ) [103] and there is evidence that during the very early phase of their recruitment (812 h after APAP) these cells can cause a temporary mild aggravation of the injury [108]

Extensive research is ongoing on a war footing to find the causative factor for AD progression, and eventually a cure

They must identify any adverse reactions or unexpected side effects