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It also plays a role in immune function and mood regulation

The pathogenesis of DN is multifaceted, involving hyperglycemia, dyslipidemia, oxidative stress, mitochondrial dysfunction, and inflammation, which collectively damage peripheral nerves

What this means in practice: ipamorelin is currently not eligible to be compounded by 503A pharmacies, but it is also no longer on the 'do not compound' Category 2 list