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Accompanied by impaired BBB integrity, these peripheral immune factors gain access to the CNS, where they mediate neuroinflammatory responses, resulting in synaptic damage and neuronal dysfunction

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Individuals with hyperhomocysteinemia may not be diagnosed due to the disorders vague symptoms

If a significant separately identifiable E&M service (e.g., new or established member office or other outpatient services [ 99201-99215 ], office or other outpatient consultation [99241-99245], emergency department service [ 99281-99285 ], preventive medicine service [ 99381-99429 ] is performed), the appropriate E&M service code should be reported in addition to the vaccine and toxoid administration codes