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doi: 10.1530/ec-17-0111 33 LaiTTLiouCWTsaiYHLinYYWuWL

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Since L-dopa is converted to dopamine in the CNS and the peri phery, peripheral conversion and systemic effects can be reduced by combining L-dopa with carbi dopa (a peripheral decarboxylation inhibitor), which does not cross the bloodbrain barrier