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This oxidative stress is not only involved in the toxicity of xenobiotics but also in the pathophysiology of various ailments like ischaemia reperfusion injury, vascular endothelium, deep injuries, organ dysfunction, shock, inflammation, sepsis, diabetic retinopathy, cancer, cognitive dysfunction, cataract, and heart disease

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Microbiol Mol Biol Rev 72(3):379412 Noguchi C, Grothusen G, Anandarajan V, Martinez-Lage Garcia M, Terlecky D, Corzo K, Tanaka K, Nakagawa H, Noguchi E (2017) Genetic controls of DNA damage avoidance in response to acetaldehyde in fission yeast

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