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However, GPX4 proved to be a more attractive candidate for silencing lipooxygenases and influencing cytokine signalling (45)

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As microbiome research progresses, a deeper understanding of its complex interactions with the immune system and other physiological processes will pave the way for more targeted, personalized microbiome-based treatments, which may eventually complement or replace conventional therapies for gastrointestinal diseases

Hum Reprod Update 18:525535 Morita Y, Perez GI, Paris F, Miranda SR, Ehleiter D, Haimovitz-Friedman A, Fuks Z, Xie Z, Reed JC, Schuchman EH et al (2000) Oocyte apoptosis is suppressed by disruption of the acid sphingomyelinase gene or by sphingosine-1-phosphate therapy