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TNF-alpha as a therapeutic target in inflammatory disorders, ischemia-reperfusion injury and trauma

Indeed, it was clearly shown that the antioxidant N-acetyl-L-cysteine (NAC) can inhibit eryptosis in vitro [116] and significantly prolong the half-life of circulating mouse erythrocytes in vivo [72] presumably by interfering with efferocytosis of eryptotic cells

The parameters of the OPLS-DA score plot obtained from these two groups were R 2 Y(cum) = 0.95 and Q 2 (cum) = 0.067, which indicated excellent fitness and acceptable reliability (Fig