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[DOI] [PMC free article] [PubMed] [Google Scholar] 23.Li M., Cui M., Li G., Liu Y., Xu Y., Eftekhar S.P., Ala M

Healing is more than just making tissue grow, its also doing it in the right place, the right amount, at the right time

In this Review, we focus on advances in our understanding of inhibition of the HGF/c-MET pathway in patients with gastro-intestinal cancers, the prominent challenges facing the clinical translation and implementation of agents targeting HGF/c-MET, and discuss the various efforts, and associated obstacles to the discovery and validation of biomarkers that will enable patient stratification in this context