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52 Interestingly, folate supplementation in isolation was found to be approximately one-third as effective as metformin in reducing insulin resistance and preventing T2DM 52 in the populations examined

If there were no quarters for which the manufacturer was required to report AMP under section 1927(b)(3) of the Act in the applicable period for a drug or biological that meets the definition of a Part D rebatable drug, we proposed CMS would exclude such drug or biological from Part D drug inflation rebate calculations