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The mechanical hypersensitivity caused by BTZ can be substantially reduced through the use of Ca 2+ channel blockers, such as tramadol, pregabalin, and ethosuximide (Yamamoto et al., 2015)

Stromal fibrin further shapes the immune infiltration landscape by acting as both a physical barrier and biochemical niche that restricts CD8 + T cell and tumor-associated macrophage penetration from the tumor stroma into the tumor parenchyma (171)

The observed biochemical differences between vaccinated and unvaccinated patients expand the current understanding of the protective effects of measles vaccination