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pylori Eradication Part of triple therapy (PPI + 2 antibiotics) Prevention Stress ulcer prophylaxis in critically ill patients Prevention of upper GI bleeding in high-risk patients on NSAIDs Dosage (Exam Favorite) Standard adult dose examples: Omeprazole 20 mg once daily (GERD) Pantoprazole 40 mg once daily (ulcer prophylaxis) Duration depends on indication (usually 48 weeks for GERD/ulcers) Adverse Effects Common: Headache, nausea, diarrhea, abdominal pain Long-term use: Vitamin B12 deficiency Hypomagnesemia Increased risk of fractures Risk of C