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Interestingly, the pharmacological inhibition of GSK-3 by lithium activates NrF2, providing plausibility for certain aspects of lithiums mechanism of action to occur through ferroptosis inhibition through the GSK-3/ NrF2 pathway [173]

[] Increased or normal HbA 1 C concentration can be found in IAS because of fluctuations in glucose concentration as transient hyperglycemic episodes are interspersed with periods of hypoglycemia

doi: 10.1523/JNEUROSCI.4906-05.2006 157 KanagawaTTomimatsuTHayashiSShiojiMFukudaHShimoyaKet al

1,2 A variety of chemotherapy classes, with varying effects by agent within a class, are known neurotoxins with a different affinity for nerves ( Table 1 )