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327 CR may prevent AD by lowering serum tyrosine levels to reverse the exhaustion of tyrosyl-tRNA synthetase (TyrRS) and upregulating the sirtuin pathway, which attenuates the amyloidogenic processing of amyloid- protein precursor (APP), as confirmed by in vivo and in vitro models

I., El-Zanfaly, M

A tolerable upper intake level (UL)the amount you can safely take without risk of severe side effectswas never set for it because it has a low potential for toxicity, and the body does not store it in excess (NIH-a, 2021)