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Besides, as indicated specifically in skin wound healing (Tkalcevic et al., 2007), BPC 157 half-life is long enough to exert a therapeutically stimulating effect on connective tissue growth (Tkalcevic et al., 2007)

In human skin fibroblasts, Nrf2-driven antioxidant enzyme expression translated into: Reduced intracellular ROS Improved mitochondrial membrane potential Protection against senescence-associated cell damage [36] In human gingival and periodontal stem cells, Epitalon significantly reduced aging biomarkers such as p16 and p21, decreased ROS levels, and preserved mitochondrial function, even under stress [42]