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Severe cardiac damage occurred when given these mice a high-iron diet and hypertrophic cardiomyopathy, with typical features of ferroptosis, which were rescued by administration of Fer-1 [72]

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However, despite these substances are able to interfere with iodine uptake in the thyroid, the consumption of reasonable amounts of foods containing goitrogens is not a concern for people who have adequate iodine intakes and eat a variety of foods, and there are no contraindications to their consumption, as detailed below [53]

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