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[1] [3] The standard UK treatment involves hydroxocobalamin 1mg intramuscular injections, with dosing regimens typically consisting of initial loading doses (e.g., every other day for two weeks) followed by maintenance doses every 2-3 months for conditions like pernicious anaemia

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A typical preventive regimen is 1,000 mcg administered intramuscularly once monthly, though some patients benefit from more frequent dosing depending on baseline status and symptoms

Injection delivers the highest systemic bioavailability the clear choice for musculoskeletal repair, tendon healing, and any target tissue outside the GI tract