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In summary, translation of mechanistic insights into clinical applications remains a dynamic frontier

Serine and glycine metabolism, derived from glycolytic 3-phosphoglycerate, provide advantages for cell growth, such as nucleotide synthesis, DNA methylation, glutathione production and NADPH generation

Biochim Biophys Acta 1709:4557 Gaitonde MK (1967) A spectrophotometric method for the direct determination of cysteine in the presence of other naturally occurring amino acids

[] For example, NRF1 regulates key factors required to maintain mtDNA, including mitochondrial transcription factor A (TFAM) and mitochondrial transcription factor B2 (TFB2M)