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They also demonstrated that Kglu could be regulated by sirtuin 5 (SIRT5) and nutrient and showed that glutaryl-CoA could directly lead to non-enzymatic Kglu

91(5):e463e471

Pb 2+ also activates the synthesis and secretion of the proinflammatory cytokine IL-8 through a nuclear factor erythroid 2-related factor 2 (Nrf2)-dependent mechanism involved in the synthesis of xenobiotic-metabolizing enzymes (Metryka et al