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Either way, you're probably wondering what the big deal is

This accumulation disrupts membrane integrity, ultimately inducing ferroptosis (Figure 1A)

The study was supported by grants from the Investigation Committee on Ossification of Spinal Ligaments, Public Health Bureau of the Japanese Ministry of Labor, Health and Welfare, and four grants-in-aid for Scientific Research (#25K12523, #25K12454, #25K20005, #23K08628)