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Importance of Early Detection and Annual Screening for Peripheral Neuropathy Annual screening for PN is recommended for all patients, with increased screening advised for those with comorbid conditions such as obesity, prediabetes, non-alcoholic steatohepatitis (NASH), and macronutrient deficiencies, including individuals diagnosed with established diabetes

Vitamin B12 is a key player in energy metabolism, aiding in the conversion of food into energy

Moreover, silencing of PNPLA2 dramatically reduces breast cancer cell invasiveness (210, 211)

Sleep disruption and pain can reinforce each other, worsening fatigue and functioning