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83(5):819841 pathology was established by methionine cholinedefi- cient diet or orotic acid addition

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Yuan et al (171) reported that Keap1 mutations are relatively common in HNSCC, and that a mutation in or lack of Keap1 inhibits ferroptosis in HNSCC by increasing NAD(P)H quinone dehydrogenase 1 (NQO1) levels through NRF2 activation