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Together, excessive and reduced production of neuro-toxic and -protective kynurenines, respectively, may exacerbate excitotoxicity and neuroinflammation, establishing a feed-forward cycle of KP dysregulation, 5-HT depletion, HPA axis hyperactivity, and increased vulnerability to MDD

Use this product in conjunction with food as part of a healthy, balanced diet, not as a substitute for such

HUVECs were incubated with p-cresol at 25 g/mL for 24 h, resulting in the generation of EMVs, which interfere with endothelial repair processes by decreasing the migratory capacity and the ability to form new vessels and by increasing cell senescence

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