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Identifying these phenotypes enables patient stratification and supports the development of targeted therapeutic strategies aligned with precision-medicine principles

doi: 10.3389/fendo.2018.00476 102 ZhouX.ZhangY.WuX.WanD.YinY

However, various preclinical studies showed that FGFR signaling has a significant impact on GB progression ( Infigratinib monotherapy was tested on twenty-six rGB patients in a phase 2 trial, and it showed limited efficacy overall