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Anti-CD42a-PE positive events with reduced size in comparison to control cells, identified in a FFC/SSC-plot, were defined as microparticles and expressed as percentage of all anti-CD42a-PE-positive events measured

GPCR-specific autoantibody signatures are associated with physiological and pathological immune homeostasis

Future research should prioritize personalized VNS therapies, leveraging closed-loop systems integrated with multimodal biomarkers (e.g., EEG-gated taVNS) to dynamically optimize stimulation in real-time (123)

Clinical translation of the developed PLGA-based nanosystems encapsulating conventional drugs and/or bioactive phytochemicals remains a challenge due to limited clinical trials validating the safety and efficacy of PLGA nano-systems