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Regulation of hepatic genes related to lipid metabolism and antioxidant enzymes by sodium butyrate supplementation

This effect is accomplished through the selective inhibition of the anti-apoptotic protein Bcl-2 expression, while significantly upregulating the activity levels of the pro-apoptotic protein Bax and the apoptotic execution factor caspase-9, thereby promoting apoptosis (Safarbalou et al., 2024)