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Fully appreciating both neutralizing and extra-neutralizing antibody functions in the control of SARS-CoV-2 infection will pave the way to the rational design of effective vaccines and therapeutics

8 weeks (0.251.0 mg/wk): ~1 vial 12 weeks (gradual to 1.7 mg/wk): ~2 vials 16 weeks (gradual to 2.44.5 mg/wk): ~3 vials Insulin Syringes (U-100, 1 mL) Per week: 1 syringe (once-weekly dosing) 12 weeks: 12 syringes 24 weeks: 24 syringes 48 weeks: 48 syringes Bacteriostatic Water (10 mL bottles) Use 2.0 mL (gradual) or 1.0 mL (advanced) per vial for reconstitution

To prevent swelling, intra-articular injections were administered weekly from the second to the fifth week post-operatively

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