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Description

Haploinsufficiency of TANK-binding kinase 1 prepones age-associated neuroinflammatory changes without causing motor neuron degeneration in aged mice

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Ramachandran and Jaeschke, 2017), the role of lysosomes in APAP hepatotoxicity has been less investigated and currently is poorly understood

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it is a severe adverse effect that can limit dose and choice of chemotherapy Many substances already approved for treating neuropathic pain failed to ameliorate CIPNP in clinical trials, underlining the importance of assessing drug efficacy in CIPNP independently of other neuropathic pain states CIPNP has distinctive mechanisms that depend on the causative cytostatic drug

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