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Synaptic integrity The understanding of the neurobiological basis of depression has evolved from a focus solely on monoamine systems towards a model of disrupted synaptic connections within mood-related brain circuits, particularly those involving the prefrontal cortex and limbic system [229,230,231,232]

M., Gieling, R

Online First: 20220414] Tsai C, Hayes C, Taylor GW (2002) Glycemic control of type 2 diabetes and severe periodontal disease in the US adult population

The SPR result confirmed that EPS interacts with KEAP1 in concentration-dependently ( K D = 6.001 10 7 M), further validating the binding of EPS to KEAP1 (Fig