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The transcription factor ARNTL (aryl hydrocarbon receptor nuclear translocation factor like protein 1) is a core component of the mammalian circadian clock 17,62 , and the autophagic degradation of the circadian clock protein ARNTL depends on the cargo receptor SQSTM1

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This includes its skin brightening properties that help restore the skins natural color and tone while lightening any unwanted dark spots and blemishes

By targeting and infiltrating certain tumour cells through receptor-mediated endocytosis, VLPs can encapsulate tiny molecules or drugs that may be used to treat cancer