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When it came to analysing their results with the Poisson method, Delbrck and Luria argued 'The situation is similar to the operation of a (fair) slot machine, where the average return from a limited number of plays is probably considerably less than the input, and improbably, when the jackpot is hit, the return is much bigger than the input' (Luria, Delbrck)

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TNF-, a pleiotropic cytokine, exists in two biologically active forms: transmembrane TNF- (TMTNF-) and secretory TNF- (STNF-)

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(I) Des--carboxy prothrombin (DCP) is secreted from HCC cells and activates c-Met because it contains two structural regions that are similar to HGF (Suzuki et al., 2005

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