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Neural Regen Res 15(3):394400

Furthermore, studies have reported an aberrant activation of NRF2, a key antioxidant transcription factor involved in the regulation of critical antioxidants including glutathione, SOD, and CAT, leading to reduced antioxidant capacity (Davinelli et al., 2025) In ASD children, the oxidative stress is not only higher, but it manifests in a complicated new pattern concerning different types of ROS and antioxidants (Hirayama et al., 2020)

4.1 Cellular fate programming In contrast to traditional hydrogels that serve as passive scaffolds, smart responsive hydrogels have achieved a paradigm shift from static support to dynamic guidance in programming cell fate

Results vary from person to person but can last anywhere from six months to a year or more