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Description

Copper peptides inhibit the formation of DHT, a hormone linked to androgenetic alopecia (male pattern baldness)

R.BruneZ.YingW.et al

4A, E and F)

Numerous agents targeting the JAKs-STAT1/5, JAKs-STAT3/6, TLR4-NF-B, MAPK, PI3K-AKT-mTOR, AMPK-PPAR and Nrf2-HO-1 pathways have been shown to induce M2 macrophage polarization and/or inhibit M1 macrophage polarization (178, 179), paving the way for the development of novel therapeutic strategies targeting macrophage functions specific to CKD and associated pathologies