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In the future, by integrating AI-driven closed-loop neuromodulation, multi-target drug intervention, and neuro-microbiome precision strategies, the spatiotemporal signal network of 7nAChR and the multi-transmitter synergistic mechanism can be analyzed to achieve individualized neuro-immune treatment for diseases such as sepsis

B.IchikawaH.GarodiaP.WeerasingheP.SethiG.BhattI

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