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Results Summary: While early Phase 2 trials showed promising functional improvements (EX: increased distance walked in the 6 minute walk test in PMM patients), large Phase 3 trials have been complex and have sometimes failed to meet primary endpoints, underscoring the challenge of treating complex mitochondrial disorders

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7 Of course, most of these patients will have no hematologic or neurologic manifestations of B 12 deficiency (ie, subclinical deficiency)

The good thing is that many users have improved their energy levels after their body adjusted to the medication, or once their blood sugar levels become stable