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Description

Quintero-Villegas A, Valds-Ferrer SI

Rational protein design yields a CD20 CAR with superior antitumor efficacy compared with CD19 CAR

For instance, the expression of ChR2 in Purkinje cells, which can be induced using transgenic mutant mice, by in utero electroporation or by viral injections [107], allows precise control over action potential firing in their downstream target, the cerebellar nuclei [108] and thereby over cerebellar-evoked excitation or inhibition in the thalamus