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doi: 10.1177/1049732305276687 21

Other drugs like EZN2968 and EZN2208 are being tested to inhibit the expression of HIF1 mRNA, leading to downregulating HIF1 protein in cancer cells [326, 327]

& Buzski, G

From this synthesis, we propose restoration of copper balance using copper delivery agents in combination with chaperones/chaperone mimetics, perhaps in conjunction with the neuroprotective amino acid serine, as a promising strategy in the treatment of this incurable disease