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Kaiya H, Saito E-S, Tachibana T, Furuse M, Kangawa K (2007) Changes in ghrelin levels of plasma and proventriculus and ghrelin mRNA of proventriculus in fasted and refed layer chicks

The JAK2/STAT5 signaling pathway is activated after binding GH to its receptor, followed by transcriptional activation of IGF-1 synthesis and induction of SOCS proteins acting as a negative feedback loop ( vide supra )

The regulation of SFKs is accomplished through mechanisms involving phosphorylation, dephosphorylation, and complex intramolecular interactions that lead to SH3 and SH2 domain displacement (104, 105)