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All samples were analysed, and the data collected were blinded to the experimental conditions

LA induces gene expression changes Then, we assessed the expression levels of well-known cell cycle regulators as the member of the AP1 transcription factor complex namely c-fos, the tumor suppressor p53 and the cyclin-dependent kinase inhibitor p21 Cip1/WAF1

However, preclinical models always constitute approximations and simplifications, and therefore, results should be interpreted with caution (180)

(2004), it is important to note that butyrate serves not only as an energy source for animals but also as a signaling molecule that plays a pivotal role in regulating the bodys energy metabolism