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Disulfiram administered in a combinatorial format may be administered at a concentration ranging from about 1-100 mg/mL, from about 1 mg/mL to about 10 mg/mL

Differential behavior of mesangial cells derived from 12/15-lipoxygenase knockout mice relative to control mice

These inflammatory proximal tubular cells can significantly downregulate GSH metabolic genes, making cells more prone to ferroptosis, resulting in repair failure after kidney injury, ultimately promoting kidney fibrosis and the progression of AKI to CKD (209)

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