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Structures of Atg7-Atg3 and Atg7-Atg10 reveal noncanonical mechanisms of E2 recruitment by the autophagy E1

For example, in neurodegenerative conditions such as Alzheimer's, Parkinson's and Huntington's diseases, elevated iron levels in the central nervous system are linked to oxidative stress, lipid peroxidation and cell death, all characteristic features of ferroptosis (96)

At a certain level, ROS works as an indicator molecule for activating acclimatory/protection responses through transduction pathways, where H 2 O 2 acts as a secondary messenger 12,13

These formulations encapsulate amphotericin B as the active pharmaceutical ingredient (API)