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There are also reports of liver damage and other serious health effects

Cancer Chemother

To strike a balance between effectiveness and the risk of reducing stress, physicians should use a cautious, step-by-step approach, giving priority to dietary and lifestyle changes first, then closely monitoring antioxidant supplementation

The remaining four carbon atoms of glutamine are exported to the cytosol as malate, which, in turn, can give rise to different metabolic pathways useful for cancer cells, including the conversion into pyruvate (Scalise et al., 2017c)