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Focal and multifocal neuropathies The primary pathophysiological mechanism underlying focal and multifocal neuropathies is ischemic injury resulting from the occlusion or compromise of the vasa nervorumthe small blood vessels supplying peripheral nerves

Johnson et al., 2019), limited information is available regarding bioenergetics within the cerebrovasculature, particularly in relation to both FA uptake and fatty acid oxidation (FAO) capabilities within the context of aging and different APOE genotypes, despite the fact that cerebrovascular FAO has been suggested to be an essential process in maintaining its transport functions (Goldstein, 1979)