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1173 Inhibiting HK1 and HK2 with lonidamine has been shown to alleviate joint damage in collagen-induced arthritis models 1174 while reducing IL-1 and TNF- levels and restoring macrophage anti-inflammatory functions in RA models

doi: 10.1007/s12013-024-01379-6 103 TanRZWangCDengCZhongXYanYLuoYet al

doi: 10.1016/j.curtheres.2013.11.001

This question is increasingly relevant as GLP-1 receptor agonists like semaglutide and liraglutide become more widely prescribed for weight management in the UK