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SuYYuanJZhangFLeiQZhangTLiKet alMicroRNA-181a-5p and microRNA-181a-3p cooperatively restrict vascular inflammation and atherosclerosis

PLoS ONE 8 , e72067 (2013)

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The interplay between these regulators creates a dynamic checkpoint: mTORC1 and HIF-1 synergize to propel effector T cell responses under nutrient-rich conditions, whereas AMPK activation restrains anabolic metabolism to favor regulatory phenotypes during energy stress