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Incretin-based pharmacotherapy now offers a medical alternative, resulting in a 15 to 20% body weight loss close to that achieved with bariatric surgery and providing considerable cardiovascular benefit

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SQSTM1 is known as an ubiquitin-binding protein and promotes the aggregation of cullin3-modified caspase-8 within p62-dependent foci, leading to cell apoptosis 50

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Mulla, M.H

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Predictors of severe Crohns disease

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