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It would be plausible to assume that altered glutaminergic signaling in these principal cortico-limbic circuits may be reflected in diverse bipolar clinical symptomatology

Subsequently, pyruvate, the end product of glycolysis, is transported into the mitochondria and oxidized by PDC to generate NADH and acetyl-CoA, the latter entering the TCA cycle

The redox balance depends on many parameters, including the levels and the compartmentalization of ROS, their specific sources and subspecies and the specificity/selectivity for their targets

Combined targeting of STAT3/NF-B/COX-2/EP4 for effective management of pancreatic cancer