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Malalignment: Anatomical abnormalities like patellar maltracking, where the patella does not move smoothly within the trochlear groove, can cause uneven pressure and wear on the cartilage

If patients are to start NASCOBAL before having tolerated cyanocobalamin parenterally, consider administering an intradermal test dose of parenteral vitamin B12 to patients suspected of cyanocobalamin hypersensitivity [see Dosage and Administration (2.1)]

Image: Tatsiana Volkava/Getty Images About the Author Joyce Hendley, Staff Writer About the Reviewer Robert H

Oxidative stress occurs when the body has too many unstable molecules called pro-oxidants free radicals and reactive oxygen species (ROS)