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J Cell Mol Med 25(13):62036216 Shen J et al (2024) NAT10 promotes renal ischemia-reperfusion injury via activating NCOA4-mediated ferroptosis

Mitochondria consume over 90% of the oxygen used by cells which makes them especially vulnerable to oxidative free radical damage. Lactobacillus fermentum ME-3 provides additional antioxidant power because it also helps recycle antioxidants like vitamin C and vitamin E to their active forms

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Complementary studies have revealed that pharmacological inhibition of TrxR induces ferroptosis in malignant cells, suggesting its therapeutic potential in cancer treatment (85,86)