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Since high homocysteine levels are often the result of poor conversion of homocysteine to methionine, which is a precursor of SAMe, SAMe depletion and homocysteine accumulation usually go hand-in-hand

Food Sci Anim Resour 46 , 31 (2026)

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For depletion of endogenous Pmc4 in the absence of plasmid-derived Pmc4, cells were cultured in YEA medium containing 0.5 mM auxin